Causes+of+Medium-Chain+Ketoacyl-CoA+Thiolase

The cause of Medium-Chain Ketoacyl-CoA Thiolase is the deficiency of acetyl-CoA acyltransferase. Acetyl-CoA C-acyltransferase belongs to the thiolase family of enzymes.



In biosynthetic and degradative reactions, the substrate nucleophilically attacks the acetyl–enzyme intermediate to yield the final product and free enzyme.

=﻿Bibliography=

"Thiolase." //Wikipedia//. N.p., n.d. Web. 9 June 2011. .

"MCKAT - Medium-chain ketoacyl-CoA thiolase deficiency - Condition Details." //Newborn Screening Coding and Terminology Guide//. N.p., 25 May 2011. Web. 9 June 2011. .

"Acetyl-CoA C-acyltransferase." //Wikipedia//. N.p., 2 June 2011. Web. 9 June 2011. .